Shameik Moore
Miles Morales (voice)
Jake Johnson
Peter B. Parker (voice)
Hailee Steinfeld
Gwen Stacy (voice)
Mahershala Ali
Uncle Aaron (voice)
Brian Tyree Henry
Jefferson Davis (voice)
Lily Tomlin
Aunt May (voice)
Luna Lauren Velez
Rio Morales (voice)
Zoë Kravitz
Mary Jane (voice)
John Mulaney
Spider-Ham (voice)
Kimiko Glenn
Peni Parker (voice)
Nicolas Cage
Spider-Man Noir (voice)
Kathryn Hahn
Doc Ock (voice)
Liev Schreiber
Wilson Fisk (voice)
Chris Pine
Peter Parker (voice)
Natalie Morales
Miss Calleros (voice)
Edwin H. Bravo
Brooklyn Visions Security Guard (voice)
Oscar Isaac
Interesting Person #1 (voice)
Greta Lee
Interesting Person #2 (voice)
Jorma Taccone
Green Goblin / Last Dude (voice)
Joaquín Cosío
Scorpion (voice)
Marvin Jones III
Tombstone (voice)
Kim Yarbrough
Scientist in Cafeteria (voice)
Lake Bell
Vanessa Fisk (voice)
Jessica Mikayla Adams
Brooklyn Friend (voice)
Gredel Berrios Calladine
Brooklyn Friend (voice)
Sarah D. Cole
Brooklyn Friend (voice)
Kelby Joseph
Brooklyn Friend (voice)
Mimi Davila
Brooklyn Visions Student (voice)
Claudia Choi
Brooklyn Visions Teacher (voice)
Melanie Haynes
Brooklyn Visions Teacher (voice)
Joseph Izzo
Brooklyn Visions Teacher (voice)
Nick Jaine
Brooklyn Visions Teacher (voice)
Muneeb Rehman
Brooklyn Visions Teacher (voice)
Carlos Zaragoza
Brooklyn Visions Teacher (voice)
Post Malone
Brooklyn Bystander (voice)
David Applebee
Additional Voices (voice)
Juan Carlos Arvelo
Additional Voices (voice)
Adam Brown
Additional Voices (voice)
Jon Bruno
Additional Voices (voice)
Darcy Rose Byrnes
Additional Voices (voice)
Oscar Camacho
Additional Voices (voice)
June Christopher
Additional Voices (voice)
Alycia Cooper
Additional Voices (voice)
Michelle Jubilee Gonzalez
Additional Voices (voice)
Terrence Hardy Jr.
Additional Voices (voice)
Bridget Hoffman
Additional Voices (voice)
Rif Hutton
Additional Voices (voice)
Miguel Jiron
Additional Voices (voice)
Harrison Knight
Additional Voices (voice)
Lex Lang
Additional Voices (voice)
Donna Lynn Leavy
Additional Voices (voice)
Andrew Leviton
Additional Voices (voice)
Caitlin McKenna
Additional Voices (voice)
Scott Menville
Additional Voices (voice)
Christopher Miller
Additional Voices (voice)
Arthur Ortiz
Additional Voices (voice)
Juan Pacheco
Additional Voices (voice)
Devika Parikh
Additional Voices (voice)
Shakira Ja'nai Paye
Additional Voices (voice)
Courtney Peldon
Additional Voices (voice)
Chrystee Pharris
Additional Voices (voice)
Jacqueline Pinol
Additional Voices (voice)
Juan Pope
Additional Voices (voice)
Al Rodrigo
Additional Voices (voice)
Joseph Sanfelippo
Additional Voices (voice)
Justin Shenkarow
Additional Voices (voice)
Dennis Singletary
Additional Voices (voice)
Warren Sroka
Additional Voices (voice)
Melissa Sturm
Additional Voices (voice)
Holly Walker
Additional Voices (voice)
Jason Linere-White
Additional Voices (voice)
Ruth Zalduondo
Additional Voices (voice)
